Just had an email from LinITX.com because, months ago, I was looking at building a Mini-ITX computer to work inside the car (and monitor it when the main ignition was off).
They sell this:
http://linitx.com/product/12770
A 12v dual-power-source "UPS" for a car. Stick your ignition's 12V on one set of inputs, and a lead-acid battery on the other set and when your car is running it will use the car battery and charge the backup battery, and when it's not running, it will use the "backup" battery to ensure consistent, uninterrupted 12v power to your project.
Thought it was useful enough back then to mark when they got more stock and that's what they were emailing me about - they have them again. Obviously, you'll need to do some voltage-conversion but dual-input, self-charging, regulated power in a car seems a good match for a lot of the projects that people have planned for the Pi.