"compressed air" cans don't actually contain air at all, they contain an inert gas that is harmless in small quantities. Don't breathe it in if you can help it though.
My personal solution to this issue is to cover the fan with two layers of ladies stockings/pantyhose.
Stretch the material slightly, but not much at all.
Use super glue to hold it to a piece of cardboard or some other frame you can attach above the fan intake.
In my use, my fan sits on top of the case, so I 3D printed a friction fit cover for the fan and super glued the material to the outside. I can then remove it as necessary and dump it in a bucket of water to clean it.
Although, after almost a year, I'm yet to need to do it even once.
Either I'm lucky, or something else keeps my electronics mostly dust free, as others tend to have problems with dust that I do not.
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