It may have been said before but possibly in different terms so it didn't show up in a search.
I back up my image before mucking about with the connectivity settings for obvious reasons.
When planning a project that you intend to eventually need a large microsd card (more than 16GB -- or even 8) start with just the 8 GB card to get things configured.
An example would be a retropi project where you did not whant the bulk of USB storage and would want it eventually installed to a 128GB card. If you start with that card size then backups and restores over a card reader are going to take an hour or so, if not more.
I keep forgetting this.
Get the project up and running on the smallest card size so you can back up the image as many times as you want when fiddling with options that might brick it.