I have not used this exact product but I assume that it should be able to be used with RPi.
Neop Pixels are a bit complicated to use with RPi but doable.
Here is a short video that I made about using NeoPixels on RPi. https://www.youtube.com/watch?v=v7FoA8fZJQA
In that video I was powering the NeoPixels from the 5v pin on the RPi and that is ok if your only powering a few LEDs but if you want to power lots of LEDs like this matrix then it will need to be powered by an external power source that is capable of supplying the needed amps.
The LEDs need a supply of 5v to run and the data pin is supposed to get min of 0.7 of of the power supply (0.7 * 5v = 3.5v), the RPi data pin only outputs 3.3v so it is technically below the specs of 3.5v so many tutorial show using a level shifter to convert the 3.3v to 5v on the data pin but I have used Neopixles on RPi, ESP32 and STM32 (all 3.3v systems) and never used a level shifter just connecting the data pin to the Neoppixel strip directly and never had a problem.
To use Nowpixels on the RPi the software uses DMA transfer to the PWM channel to create all the on/off switching needed to communicate with the NeoPixels, the is exactly what the sound does to output to the speaker jack. So to use this channle for Neopixels you will need to disable the sound jack, see my earlier posted video.
Here is a link to Adafruit setup tutorial of the software https://learn.adafruit.com/neopixels-on ... i/software