Unfortunately, anyone who's ever had "pops and clicks" on a USB (or Firewire, or PCI etc.) soundcard may have found that it has little to do with the theoretical bulk transfer rate of the interface in question, but is more likely something to do with the hardware / driver implementation of that interface, or the soundcard driver, how well the operating system handles hardware interrupts, or even power saving technology being unable to respond to dynamic processing loads quickly enough. Bigger data buffers can help sometimes, but only up to a point.
For instance, CD quality audio lumbers along at a bitrate of 1.4Mb/sec (note the small "b"). This is a theoretical drop in the bucket for a USB connection that might work at a real world rate of 25MB/sec+. But - for the reasons noted above - problems still happen.