I am using both a USB 3.0 USB data stick and a USB 3.0 connected SSD along with a wireless keyboard and mouse. However, I have been using this exact setup for at least 6 months and have never experienced any issues. By exact same, I mean all cabling, peripherals, and physical location and orientation of devices. Nothing was plugged/unplugged recently, with the exception of turning off the keyboard, replacing the batteries, and turning it back on.
Other than the software update, nothing has changed with the Pi and further more, nothing has changed in the electrical environment in the house (no new equipment, routers, central vac, 100 Ton stamp presses, linear colliders, etc).
For whatever reason my Pi has had zero USB 3.0 and/or HDMI interference issues before this.