I am using a sainsmart 320x240px screen w/ touchpanel, and when I run OpenTTD, the touch panel input is rotated 180 degrees relative to the actual image: meaning when I hit exit, the cursor goes to move the window, vice versa, Y and X axes (axises?) are flipped, etc.
Here's the kicker: Xwindows is not affected!
OS: modified raspbian supplied w/ screen
Powersupply: 5VDC @ 1A max 2.2Ah battery
Raspi Models: A+, B
more available upon request