You can use the Mac as a terminal for the Pi, using SSH (command line) or VNC (GUI) over WiFi or Ethernet.
Plenty of info in the Documentation section, or search the site.
While that is true in this case, it is good practice to terminate unused inputs to logic systems. In fact many pulls are set by default:
More details here.Most GPIOs have a default pull applied.
You can use a Charge Doctor on the input or on any single USB output.